Cytokine and Chemokine Levels in Coronavirus Disease 2019 Convalescent Plasma

Abstract

The efficacy of coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) is primarily ascribed as a source of neutralizing anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. However, the composition of other immune components in CCP and their potential roles remain largely unexplored. This study aimed to describe the composition and concentrations of plasma cytokines and chemokines in eligible CCP donors.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 26, 2020
Source ID
10.1093/ofid/ofaa574

Entities

People

  • Aaron Tobian
  • Alison G Abraham
  • Andrew D. Redd
  • Andrew Pekosz
  • Arturo Casadevall
  • David P Sullivan
  • Eshan U Patel
  • Evan M Bloch
  • Kirsten Littlefield
  • M. Kate Grabowski
  • Oliver Laeyendecker
  • Ruchee Shrestha
  • Sarah E. Benner
  • Shmuel Shoham
  • Tania S. Bonny
  • Thomas C. Quinn
  • Xianming Zhu

Organizations

  • Bloomberg Philanthropies
  • Johns Hopkins Bloomberg School of Public Health
  • Johns Hopkins School of Medicine
  • Johns Hopkins University
  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
  • United States Department of Defense
  • University of Colorado

Tags

Fields of Study

  • Medicine

Readers

  • Asian Economic Studies
  • Infectious Disease/Epidemiology
  • Oncology (Cancer Research).