126. Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection and Vaccination
Abstract
T cells are central to the early identification and clearance of viral infections and support antibody generation by B cells, making them desirable for assessing the immune response to SARS-CoV-2 infection and vaccines. We combined 2 high-throughput immune profiling methods to create a quantitative picture of the SARS-CoV-2 T-cell response that is highly sensitive, durable, diagnostic, and discriminatory between natural infection and vaccination.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 01, 2021
- Source ID
- 10.1093/ofid/ofab466.126
Entities
People
- Alessandra Sottini
- Andrea Biondi
- Camille Alba
- Camillo Rossi
- Claudio Cerchione
- Clifton L Dalgard
- Damon H May
- Edward J Osborne
- Estela Paz-artal
- Eugenia Quiros-roldan
- Fabio Nicolini
- Giovanni Martinelli
- Gonazalo Carreño-tarragona
- H Jabran Zahid
- Harlan S Robins
- Helen Su
- Ian M Kaplan
- James R. Heath
- Jason D Goldman
- Jennifer N Dines
- Joaquin Martinez-lopez
- Jonathan M. Carlson
- Kerry Dobbs
- Lance Baldo
- Laura Rachele Bettini
- Luigi D Notarangelo
- Luisa Imberti
- Mariella D’angio’
- Mark Klinger
- Massimiliano Mazza
- Matthew T Noakes
- Miranda F. Tompkins
- Ottavia M Delmonte
- Paolo Bonfanti
- Rachel M. Gittelman
- Ravi Pandya
- Rebecca Elyanow
- Rocio Laguna-goya
- Ruth Taniguchi
- Santiago Barrio
- Simona Semprini
- Sudeb C Dalai
- Thomas M. Snyder
- Vittorio Sambri
Organizations
- Adaptive Biotechnologies
- Complutense University of Madrid
- Institute for Systems Biology
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
- Microsoft Research
- National Institute of Allergy and Infectious Diseases
- Uniformed Services University of the Health Sciences
- University of Bologna
- University of Brescia
- University of Washington