Multifocal calcific periarthritis with distinctive clinical and radiological features in patients with CD73 deficiency

Abstract

Arterial calcification due to deficiency of CD73 (ACDC) is a hereditary autosomal recessive ectopic mineralization syndrome caused by loss-of-function mutations in the ecto-5′-nucleotidase gene. Periarticular calcification has been reported but the clinical characterization of arthritis as well as the microstructure and chemical composition of periarticular calcifications and SF crystals has not been systematically investigated.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 21, 2021
Source ID
10.1093/rheumatology/keab270

Entities

People

  • Alessandra Brofferio
  • Blas Betancourt
  • Cornelia Cudrici
  • Cynthia St Hilaire
  • Deepak Lakshmipathy
  • Elisa A Ferrante
  • Han Wen
  • James D Katz
  • Kam A Newman
  • Katherine Carney
  • Leon J. Nesti
  • Manfred Boehm
  • Markku Miettinen
  • Mohammad H Bagheri
  • Rebecca Huffstutler
  • Richard Siegel

Organizations

  • Istituto Superiore di Sanità
  • National Cancer Institute
  • National Heart, Lung, and Blood Institute
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • National Institutes of Health
  • University of Pittsburgh
  • University of Pittsburgh School of Medicine
  • Walter Reed National Military Medical Center

Tags

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biology
  • Neurotrauma and Rehabilitation Medicine.
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