Response Inhibition in Adolescents is Moderated by Brain Connectivity and Social Network Structure
Abstract
The social environment an individual is embedded in influences their ability and motivation to engage self-control processes, but little is known about the neural mechanisms underlying this effect. Many individuals successfully regulate their behavior even when they do not show strong activation in canonical self-control brain regions. Thus, individuals may rely on other resources to compensate, including daily experiences navigating and managing complex social relationships that likely bolster self-control processes. Here, we employed a network neuroscience approach to investigate the role of social context and social brain systems in facilitating self-control in adolescents. We measured brain activation using fMRI as 62 adolescents completed a Go/No-Go response inhibition task. We found that self-referential brain systems compensate for weaker activation in executive function brain systems, especially for adolescents with more friends and more communities in their social networks. Collectively, our results indicate a critical role for self-referential brain systems during the developmental trajectory of self-control throughout adolescence.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 06, 2020
- Source ID
- 10.1093/scan/nsaa109
Entities
People
- Christopher N. Cascio
- Danielle Bassett
- Emily B Falk
- Jean M Vettel
- Joseph B Bayer
- Matthew Brook O’donnell
- Steven H Tompson
Organizations
- Alfred P. Sloan Foundation
- Army Research Office
- Institute for Scientific Interchange
- John D. and Catherine T. MacArthur Foundation
- National Institutes of Health
- National Science Foundation
- Ohio State University
- Paul G. Allen Family Foundation
- United States Army Research Laboratory
- University of Pennsylvania
- University of Wisconsin–Madison