Poor sleep correlates with biomarkers of neurodegeneration in mild traumatic brain injury patients: a CENC study
Abstract
Sleep disorders affect over half of mild traumatic brain injury (mTBI) patients. Despite evidence linking sleep and neurodegeneration, longitudinal TBI-related dementia studies have not considered sleep. We hypothesized that poor sleepers with mTBI would have elevated markers of neurodegeneration and lower cognitive function compared to mTBI good sleepers and controls. Our objective was to compare biomarkers of neurodegeneration and cognitive function with sleep quality in warfighters with chronic mTBI.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 06, 2020
- Source ID
- 10.1093/sleep/zsaa272
Entities
People
- Chen Lai
- Jessica M. Gill
- Josephine U. Pucci
- Kent Werner
- Kimbra Kenney
- Pashtun Shahim
- Ramon Diaz-Arrastia
- Risa Nakase-richardson
- Sorana Raiciulescu
Organizations
- Center for Neuroscience and Regenerative Medicine
- James A. Haley Veterans' Hospital
- National Institutes of Health
- Uniformed Services University of the Health Sciences
- United States Department of Defense
- University of Pennsylvania
- University of South Florida