Inflammatory Biomarker Association with Pulmonary Vasoconstriction Versus Blood Oxygenation in a Pig Model of Endotoxin‐Induced Pulmonary Hypertension
Abstract
Escherichia coli sepsis remains the most mortal cause of early‐onset neonatal sepsis and is characterized by an endotoxin lipopolysaccharide (LPS)‐mediated acute inflammatory response and pulmonary edema. Cytokines are increasingly being evaluated as potential biomarkers for diagnosis of sepsis and monitoring of disease severity but the timing of inflammatory changes in relation to pulmonary hypertension and pulmonary function is unclear.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2018
- Source ID
- 10.1096/fasebj.2018.32.1_supplement.lb235
Entities
People
- Catherine Uyehara
- Claudia A. Hernandez
- Dao H. Ho
- Jauchia W. Blythe
- Jillian M. Piaggione
- Lee‐ann M. Murata
- Rozalia Laczko
- Wayne M. Ichimura
- William J. Sherman
Organizations
- AMC
- Tripler Army Medical Center
- United States Army Medical Command