Hemodynamic Determinants of Cardiac Interoception
Abstract
. Many of the sensory receptors that encode touch, temperature, pain, and visual or auditory cues are well known. These exteroceptive receptors allow us to respond to external threats from the environment. The interoceptive sensory receptors that allow us to identify threats within the internal milieu, such as changes of our heart rate brought about by fright, gastric fullness with satiety, or breathing difficulty from increased respiratory resistance are not known. We postulated that the mechanosensitive piezo receptors in the heart are responsible for cardiac interoception in humans. If true, individual contrasts in cardiac contractility among the population sensed by these stretch receptors in the heart could explain the ability of some men and women to “feel” their heart rate without taking their pulse.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 01, 2022
- Source ID
- 10.1096/fasebj.2022.36.s1.r5601
Entities
People
- Jonathon Beckman
- Judy Taha
- Ryan Woodman
- Wael Taha
- Warren Lockette
- Yong Li
Organizations
- United States Department of Defense
- University of California, Davis
- Wayne State University