Cats that successfully vent gastric acid‐derived CO2 exhibit different muscle activation than those that do not (1178.13)
Abstract
We previously reported that inhaling 10% CO2 increased efflux of CO2‐laden gas from cats’ stomachs. Anesthetized cats were surgically instrumented: we measured electromyograms (EMGs) from respiratory and oropharyngeal muscles, including crural diaphragm (CD) and upper esophageal sphincter (UES), as well as tracheal and esophageal gas flow and composition. Animals were exposed to six, 10‐min bouts of 10% CO2 breathing separated by 10 min air breathing. All animals produced gastric CO2 and expelled it during cough, but half failed to expel CO2 during normal breathing (non‐responders (NR) n=4). Responders (Re, n=4) expelled gastric CO2 during normal breathing. EMGs were compared by t‐test to determine if different levels of muscle activation were present in the two groups. EMG signals were rectified and analyzed breath‐by‐breath for inspiratory (ins) and expiratory (exp) values and are presented as mean percent of the highest value observed for that animal ± SE.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2014
- Source ID
- 10.1096/fasebj.28.1_supplement.1178.13
Entities
People
- Ashley Mortensen
- Bruce Lindsey
- David Baekey
- Donald Bolser
- Heather Held
- Jay B. Dean
- Justine Nicholas
- Melanie Rose
- Paul Davenport
- Teresa Pitts
Organizations
- National Institutes of Health
- Office of Naval Research
- University of Florida
- University of South Florida