Unequal impact and spatial aggregation distort COVID-19 growth rates

Abstract

The COVID-19 pandemic has posed unprecedented challenges to public health world-wide. To make decisions about mitigation strategies and to understand the disease dynamics, policy makers and epidemiologists must know how the disease is spreading in their communities. Here we analyse confirmed infections and deaths over multiple geographic scales to show that COVID-19’s impact is highly unequal: many regions have nearly zero infections, while others are hot spots. We attribute the effect to a Reed–Hughes-like mechanism in which the disease arrives to regions at different times and grows exponentially at different rates. Faster growing regions correspond to hot spots that dominate spatially aggregated statistics, thereby skewing growth rates at larger spatial scales. Finally, we use these analyses to show that, across multiple spatial scales, the growth rate of COVID-19 has slowed down with each surge. These results demonstrate a trade-off when estimating growth rates: while spatial aggregation lowers noise, it can increase bias. Public policy and epidemic modelling should be aware of, and aim to address, this distortion.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 22, 2021
Source ID
10.1098/rsta.2021.0122

Entities

People

  • Keith Burghardt
  • Kristina Lerman
  • Siyi Guo

Organizations

  • Defense Advanced Research Projects Agency
  • Information Sciences Institute
  • University of Southern California

Tags

Fields of Study

  • Biology

Readers

  • Computational Modeling and Simulation
  • Economics
  • Plasma Physics.