From mechanobiology to developmentally inspired engineering
Abstract
The field of mechanobiology emerged based on the recognition of the central role that physical forces play in development and physiology. In this article, which is based on a lecture I presented at the 2018 Royal Society meeting on Mechanics of Development, I review work from my laboratory carried out over the 40 years which helped to birth this field. I will also describe how we are leveraging the fundamental design principles that govern mechanoregulation to develop new experimental tools and organ-engineering approaches as well as novel mechanotherapeutics.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 24, 2018
- Source ID
- 10.1098/rstb.2017.0323
Entities
People
- Donald E. Ingber
Organizations
- Boston Children's Hospital
- Center for Scientific Review
- Defense Advanced Research Projects Agency
- Food and Drug Administration
- Harvard Medical School
- Harvard University