Brief Report: Genetics of Alcoholic Cirrhosis—GenomALC Multinational Study
Abstract
The risk of alcohol‐related liver cirrhosis increases with increasing alcohol consumption, but many people with very high intake escape from liver disease. We postulate that susceptibility to alcoholic cirrhosis has a complex genetic component and propose that this can be dissected through a large and sufficiently powered genomewide association study (GWAS).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 14, 2015
- Source ID
- 10.1111/acer.12693
Entities
People
- Ann K. Daly
- Bertrand Nalpas
- Chi Westerhold
- Christopher P. Day
- Devanshi Seth
- Felix Stickel
- For The Genomalc Consortium
- Gregory J. Botwin
- Heather J. Cordell
- Helmut K. Seitz
- John B. Whitfield
- Khairunnessa Rahman
- Lawrence Lumeng
- Michael Soyka
- Paul S. Haber
- Philippe Mathurin
- Sebastian Mueller
- Steven Masson
- Suthat Liangpunsakul
- Tatiana Foroud
- Tiebing Liang
- Timothy R. Morgan
Organizations
- Centenary Institute
- Foundation for the National Institutes of Health
- French National Institute of Health and Medical Research
- Heidelberg University
- Indiana University – Purdue University Indianapolis
- National Institute on Alcohol Abuse and Alcoholism
- Newcastle University
- QIMR Berghofer Medical Research Institute
- Royal Prince Alfred Hospital
- United States Department of Defense
- United States Department of Veterans Affairs
- University Hospital Zurich
- University of Sydney