Effects of Oxytocin Administration on Cue‐Induced Craving in Co‐occurring Alcohol Use Disorder and PTSD: A Within‐Participant Randomized Clinical Trial
Abstract
Individuals with alcohol use disorder (AUD) are much more likely to meet criteria for posttraumatic stress disorder (PTSD) than the general population. Compared to AUD alone, those with comorbid AUD‐PTSD experience worse outcomes. Prior literature suggests that oxytocin, a hypothalamic neuropeptide, may be effective in the treatment of both AUD and PTSD when administered intranasally, although specific mechanisms remain elusive.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 06, 2019
- Source ID
- 10.1111/acer.14217
Entities
People
- Andrea Niles
- Aoife O'donovan
- Christopher S Stauffer
- David Leung
- Jin‐hui Wen
- Joshua D. Woolley
- Lily Radanovich
- Nathan K. Meinzer
- Steven L. Batki
- Tyler Morrison
Organizations
- San Francisco VA Medical Center
- United States Department of Defense
- United States Department of Veterans Affairs
- University of British Columbia
- University of California, San Francisco