Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers

Abstract

To investigate whether trauma exposure moderates the genetic correlation between substance use disorders and psychiatric disorders, we tested whether trauma exposure modifies the association of genetic risks for mental disorders with alcohol misuse and nicotine dependence (ND) symptoms.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 11, 2017
Source ID
10.1111/acps.12843

Entities

People

  • H. R. Kranzler
  • Hongping Zhao
  • Jason Kaufman
  • Joel Gelernter
  • M. B. Stein
  • R. C. Kessler
  • R. J. Ursano
  • Renato Polimanti

Organizations

  • Harvard Medical School
  • Johns Hopkins School of Medicine
  • Kennedy Krieger Institute
  • National Institute of Mental Health
  • National Institutes of Health
  • Uniformed Services University of the Health Sciences
  • United States Department of Defense
  • United States Department of Health and Human Services
  • University of California, San Diego
  • University of Pennsylvania
  • VA San Diego Healthcare System
  • Yale School of Medicine
  • Yale University

Tags

Fields of Study

  • Medicine
  • Psychology

Readers

  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Molecular Genetics

Technology Areas

  • Biotechnology