Down‐regulation of metabolic pathways could offset the poor prognosis conferred by co‐existent diabetes mellitus in pancreatic (head) adenocarcinoma
Abstract
Pancreatic ductal adenocarcinoma (PDAC) patients with diabetes mellitus (DM) have poor overall survival. Underlying mechanisms have not been fully clarified. This presents an opportunity for precision‐oncology for which we systematically analysed publicly‐available PDAC transcriptome data.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 13, 2021
- Source ID
- 10.1111/ans.17194
Entities
People
- Madhura Ketkar
- Nilesh Gardi
- Ross A. Mckinnon
- Savio G Barreto
- Shilpee Dutt
- Stephen J Pandol
Organizations
- Advanced Centre for Treatment, Research and Education in Cancer
- Cancer Council SA
- Cedars-Sinai Medical Center
- Flinders Medical Centre
- Flinders University
- Foundation for the National Institutes of Health
- Homi Bhabha National Institute
- Tata Memorial Centre
- United States Department of Defense