Hyperbaric oxygen should be used for carbon monoxide poisoning
Abstract
This short review addresses the mechanisms of injury mediated by carbon monoxide (CO) and current information on efficacy of hyperbaric oxygen therapy (HBOT). Recent clinical series involving large, country‐wide databases and prospective randomized trials are summarized. We conclude that there is an abundance of basic science and preclinical and clinical research supporting the use of HBOT for acute CO poisoning. With appropriate consideration for pathology and therapeutic mechanisms, HBOT at a dose of 2.5–3.0 atm absolute is a necessary treatment for this toxidrome.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 01, 2022
- Source ID
- 10.1111/bcp.15605
Entities
People
- Kinjal Sethuraman
- Stephen R. Thom
Organizations
- Office of Naval Research