Parsimony optimization of phylogenetic networks

Abstract

An algorithm is described for the optimization of character data (e.g. qualitative, nucleic acid sequence) on softwired phylogenetic networks. The algorithm presented here is an extension of those developed for trees under the parsimony criterion and can form the basis for phylogenetic network search procedures. Although the problem is (in general) an NP‐Hard optimization, the resolution‐based algorithm we describe here capitalizes on the significant amount of shared structure in sub‐graphs containing network edges, reducing the execution time and allowing for the analysis of empirical datasets.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 19, 2023
Source ID
10.1111/cla.12552

Entities

People

  • Alexander J. Washburn
  • Ward C. Wheeler

Organizations

  • American Museum of Natural History
  • City University of New York
  • Defense Advanced Research Projects Agency

Tags

Readers

  • Graph Algorithms and Convex Optimization.
  • Regression Analysis.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology