Flexible, high‐resolution cortical arrays with large coverage capture microscale high‐frequency oscillations in patients with epilepsy
Abstract
Effective surgical treatment of drug‐resistant epilepsy depends on accurate localization of the epileptogenic zone (EZ). High‐frequency oscillations (HFOs) are potential biomarkers of the EZ. Previous research has shown that HFOs often occur within submillimeter areas of brain tissue and that the coarse spatial sampling of clinical intracranial electrode arrays may limit the accurate capture of HFO activity. In this study, we sought to characterize microscale HFO activity captured on thin, flexible microelectrocorticographic (μECoG) arrays, which provide high spatial resolution over large cortical surface areas.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 17, 2023
- Source ID
- 10.1111/epi.17642
Entities
People
- Agrita Dubey
- Alex Efstathios Voinas
- Bijan Pesaran
- Breonna Ferrentino
- Charles Wang
- Chia-Han Chiang
- Daniel Friedman
- Derek G Southwell
- Florian Solzbacher
- Gregory B Cogan
- James Sun
- Jonathan Viventi
- Justin A. Blanco
- Katie E. Wingel
- Katrina Barth
- Matthew Vestal
- Michael M. Haglund
- Michael Trumpis
- Orrin Devinsky
- Sasha Devore
- Saurabh R Sinha
- Shaoyu Qiao
- Shervin Rahimpour
- Stephen C. Harward
- Suseendrakumar Duraivel
- Werner Doyle
Organizations
- American Epilepsy Society
- Army Research Office
- Centers for Disease Control and Prevention
- Duke University
- Epilepsy Foundation
- Esther A. & Joseph Klingenstein Fund
- Grossman School of Medicine
- National Institutes of Health
- National Science Foundation
- New York University
- Office of Naval Research
- Templeton World Charity Foundation
- The Vilcek Foundation
- Tuberous Sclerosis Alliance
- United States Department of Defense
- United States Naval Academy
- University of Pennsylvania
- University of Utah