The influence of interleukin‐7 receptor α‐chain haplotypes on outcome after allogeneic hematopoietic cell transplantation

Abstract

We investigated the influence of IL‐7 receptor α‐chain (IL‐7Rα) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to ‘dilution’ of SNPs into haplotypes.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 29, 2014
Source ID
10.1111/iji.12158

Entities

People

  • B. Broux
  • Klaus-Robert Müller
  • L. P. Ryder
  • M. Haagenson
  • N. Hellings
  • P. Stinissen
  • Stephen R. Spellman
  • Tianhong Wang
  • Z. Shamim

Organizations

  • Center for International Blood and Marrow Transplant Research
  • Danish Cancer Society
  • Hasselt University
  • Health Resources and Services Administration
  • Medical College of Wisconsin
  • National Cancer Institute
  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
  • Office of Naval Research
  • Research Foundation - Flanders
  • Uppsala University Hospital

Tags

Fields of Study

  • Medicine

Readers

  • Canine Service Warrior Training Program for Wounded Warriors in the Veterinary Industry, Supported by Donors.
  • Immunology and Pathology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech