Simvastatin cream alleviates dermal fibrosis in a rabbit ear hypertrophic scar model

Abstract

Hypertrophic scars (HTS) result from injury to the skin and represent a clinical burden with limited treatment options. Previously, we demonstrated that statin drugs could attenuate HTS formation, but convenient topical delivery and retention of these drugs at the wound site remains a challenge.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 22, 2022
Source ID
10.1111/jocd.15142

Entities

People

  • Adrian E. Rodrigues
  • Chun Hou
  • David M Dolivo
  • Eugene Chung
  • Kai P. Leung
  • Lauren Sun
  • Robert Galiano
  • Seok Jong Hong
  • Thomas Mustoe
  • Yingxing Li

Organizations

  • Guangzhou Medical University
  • Northwestern University
  • United States Army

Tags

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.