Semiautomated Assessment of the Anterior Cingulate Cortex in Alzheimer's Disease

Abstract

The anterior cingulate cortex (ACC) is involved in several cognitive processes including executive function. Degenerative changes of ACC are consistently seen in Alzheimer's disease (AD). However, volumetric changes specific to the ACC in AD are not clear because of the difficulty in segmenting this region. The objectives of the current study were to develop a precise and high‐throughput approach for measuring ACC volumes and to correlate the relationship between ACC volume and cognitive function in AD.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 14, 2019
Source ID
10.1111/jon.12598

Entities

People

  • Flora Jung
  • Nagalingam Rajakumar
  • Robert Bartha
  • Samaneh Kazemifar

Organizations

  • AbbVie
  • Alzheimer's Association
  • Alzheimer's Disease Neuroimaging Initiative
  • Alzheimer's Drug Discovery Foundation
  • BioClinica
  • Biogen
  • Bristol-Myers Squibb
  • Chiron Corporation
  • Eisai (South Korea)
  • Eli Lilly and Company
  • GE HealthCare
  • Innogenetics
  • Laboratoires Servier
  • Merck & Co.
  • Meso Scale Diagnostics (United States)
  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • Natural Sciences and Engineering Research Council
  • Northern California Institute for Research and Education
  • Pfizer
  • Takeda Pharmaceutical Company
  • United States Department of Defense
  • Western University

Tags

Fields of Study

  • Medicine

Readers

  • Computer Vision.
  • Molecular Genetics
  • Neuroscience