Vasoactive effect of fibronectin‐derived epiviosamine‐1 and related peptides in quiescent and stress models
Abstract
Following thermal burn injury, plasma fibronectin degrades within the interstitium; one possible product is EVA‐1, PSHISKYILRWRPK found within the FNIII1. EVA‐1 ameliorates thermal burn injury progression, and binds to and enhances PDGF‐BB in promoting cell metabolism, growth and survival; shorter related peptides lose these abilities. Here we study the effect of EVA‐1 and shorter peptides for their vasoactivity under quiescent and stress conditions.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 01, 2017
- Source ID
- 10.1111/micc.12369
Entities
People
- Anthony M. Dewar
- Fubao Lin
- Mary D Frame
- Richard A F Clark
Organizations
- American Heart Association
- Armed Forces Institute of Regenerative Medicine
- National Institutes of Health
- Stony Brook University