Differential arterial and venous endothelial redox responses to oxidative stress

Abstract

Oxidative stress is a central event linked with endothelial dysfunction and inflammation in several vascular pathologies, marked by over‐production of ROS and concomitant decreases in antioxidants, for example GSH. Here, we distinguish endothelial oxidative stress regulation and associated functional disparities in the two main vascular conduits, (arteries and veins) following decreases in GSH.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 23, 2018
Source ID
10.1111/micc.12486

Entities

People

  • A. Wayne Orr
  • Amir M. Kaskas
  • Ankur Khanna
  • Bandana Shrestha
  • Christopher B. Pattillo
  • Jonathan Steven Alexander
  • Matthew D Woolard
  • Priya K. Prasai
  • Sunjay Letchuman
  • Vijay Letchuman

Organizations

  • American Heart Association
  • Louisiana State University
  • National Heart, Lung, and Blood Institute
  • National Institute of General Medical Sciences
  • United States Department of Defense

Tags

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology