Sacral nerve stimulation ameliorates colonic barrier functions in a rodent model of colitis
Abstract
The mucosal barrier damage is recognized as one of the key factors in the pathogenesis of colitis. While sacral nerve stimulation (SNS) was reported to have therapeutic potential for colitis, its mechanisms of actions on colonic permeability remained largely unknown.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 14, 2020
- Source ID
- 10.1111/nmo.13916
Entities
People
- Jiande D Z Chen
- Jieyun Yin
- Lei Tu
- Payam Gharibani
Organizations
- Defense Advanced Research Projects Agency
- Johns Hopkins University