2‐oxoglutarate‐dependent dioxygenases drive expansion of steroidal alkaloid structural diversity in the genus Solanum

Abstract

Solanum steroidal glycoalkaloids (SGAs) are renowned defence metabolites exhibiting spectacular structural diversity. Genes and enzymes generating the SGA precursor pathway, SGA scaffold and glycosylated forms have been largely identified. Yet, the majority of downstream metabolic steps creating the vast repertoire of SGAs remain untapped.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 28, 2022
Source ID
10.1111/nph.18064

Entities

People

  • Adam Jozwiak
  • Adi Doron‐faigenboim
  • Arthur Schaffer
  • Asaph Aharoni
  • Ashok Giri
  • Bekele Abebie
  • Guy Wizler
  • Ilana Rogachev
  • Marina Petreikov
  • Ofir Ramot
  • Prashant D. Sonawane
  • Ranjit S. Barbole
  • Sachin Ashruba Gharat
  • Sagit Meir
  • Sayantan Panda
  • Tali Scherf
  • Tamar Unger
  • Yana Kazachkova

Organizations

  • Academy of Scientific and Innovative Research
  • Council of Scientific and Industrial Research
  • Leona M. and Harry B. Helmsley Charitable Trust
  • Weizmann Institute of Science

Tags

Readers

  • Materials Science and Engineering.
  • Prostate Cancer Biology.
  • Systems Analysis and Design