Guillain–Barré syndrome associated with resistant cytomegalovirus infection after face transplantation
Abstract
A 39‐year‐old male, who received a facial allograft (cytomegalovirus [CMV] donor‐seropositive, recipient‐seronegative), developed multidrug‐resistant CMV infection despite valganciclovir prophylaxis (900 mg/day) 6 months post transplantation. Lower extremity weakness with upper and lower extremity paresthesias developed progressively 11 months post transplantation, coinciding with immune control of CMV. An axonal form of Guillain–Barré syndrome was diagnosed, based on electrophysiological evidence of a generalized, non‐length‐dependent, sensorimotor axonal polyneuropathy. Treatment with intravenous immunoglobulin led to complete recovery without recurrence after 6 months.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2016
- Source ID
- 10.1111/tid.12516
Entities
People
- A.a. Amato
- A.a. Sharfuddin
- B. Pomahac
- E.m. Bueno
- F.m. Marty
- I. Hadad
- M. Alhefzi
- M. Kueckelhaus
- M.a. Aycart
- P. Malla
- R.j. Snook
- Sean R. Fischer
Organizations
- Harvard Medical School
- Indiana University
- United States Department of Defense