Additive solution‐7 reduces the red blood cell cold storage lesion
Abstract
Transfusion of long‐stored red blood cells (RBCs) is associated with decreased in vivo RBC recovery, delivery of RBC breakdown products, and increased morbidity and mortality. Reducing the burden of this RBC “storage lesion” is a major challenge in transfusion medicine. Additive solution‐7 (AS‐7) is a new RBC storage solution designed to improve RBC metabolism by providing phosphate and increasing buffering capacity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 19, 2014
- Source ID
- 10.1111/trf.12867
Entities
People
- Alan H. Siegel
- John R Hess
- Jose A Cancelas
- Larry J. Dumont
- Lou A. Maes
- Louise Herschel
- Majid Zia
- Neeta Rugg
- Pamela H. Whitley
- Zbigniew M. Szczepiokowski
Organizations
- American Red Cross
- Geisel School of Medicine
- United States Army Medical Research and Development Command
- University of Cincinnati
- University of Washington