Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trial

Abstract

The Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trial was a randomized clinical trial comparing survival after transfusion of two different blood component ratios for emergency resuscitation of traumatic massive hemorrhage. Transfusion services supporting the study were expected to provide thawed plasma, platelets, and red blood cells within 10 minutes of request.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 30, 2015
Source ID
10.1111/trf.13098

Entities

People

  • Barbara C. Tilley
  • Bryan A. Cotton
  • Deborah J. Novak
  • Eberhard W. Fiebig
  • Erin E. Fox
  • Ira A. Shulman
  • Janice M. Nelson
  • Jeanette M. Podbielski
  • Jeannie L. Callum
  • Jennifer A. Daniel‐johnson
  • Jerome L. Gottschall
  • John B Holcomb
  • John R Hess
  • Kenji Inaba
  • Magali J. Fontaine
  • Marisa B. Marques
  • Martin A. Schreiber
  • On Behalf Of The Proppr Study Group
  • Patricia M. Carey
  • Rhonda K. Cooke
  • Richard M. Scanlan
  • Sandro Rizoli
  • Sarah Baraniuk
  • Sherri Flax
  • Veda Duncan
  • Yu Bai

Organizations

  • Canadian Institutes of Health Research
  • Defence Research and Development Canada
  • Keck School of Medicine of USC
  • Medical College of Wisconsin
  • National Heart, Lung, and Blood Institute
  • Oregon Health & Science University
  • Sunnybrook Health Sciences Centre
  • The Regional Medical Center
  • United States Department of Defense
  • University of Alabama at Birmingham
  • University of Arizona
  • University of California, San Francisco
  • University of Cincinnati
  • University of Southern California
  • University of Texas at Austin
  • University of Toronto
  • University of Washington

Tags

Readers

  • Cardiovascular Physiology
  • Immunology
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