Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients
Abstract
Several retrospective studies have suggested that transfusion with red blood cells (RBCs) stored for longer periods is associated with increased mortality. The Age of Blood Evaluation (ABLE) study randomized subjects to receive fresh vs. standard issue RBC units and showed no difference in the primary or secondary endpoints of mortality or change in multi‐organ dysfunction syndrome (MODS) score.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 18, 2019
- Source ID
- 10.1111/trf.15250
Entities
People
- Ali Danesh
- Anne M. Guiltinan
- Avani Shah
- Avril Adelman
- Heather C. Inglis
- Jacques Lacroix
- John W. Heitman
- Ken Schechtman
- Mitchell J. Cohen
- Nareg H. Roubinian
- Philip C Spinella
- Philip J Norris
- Ryan Vilardi
- Sheila M. Keating
Organizations
- Department of Surgery
- National Heart, Lung, and Blood Institute
- United States Department of Defense
- University of California, San Francisco
- Washington University in St. Louis