Platelet enhancement of bacterial growth during room temperature storage: mitigation through refrigeration
Abstract
Due to high risk of septic transfusion reactions arising from bacterial contamination, US Food and Drug Administration regulations currently limit platelet storage to 5 days at room temperature (RT). However, blood culturing methods can take up to 7 days to detect bacteria, allowing transfusion of potentially contaminated units. Thus, cold storage (CS) may be a viable means of extending shelf life and improving safety.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 01, 2019
- Source ID
- 10.1111/trf.15255
Entities
People
- Andrew P Cap
- Bernard P Arulanandam
- Kevin Akers
- Patrick M. Ketter
- Robin Kamucheka
Organizations
- United States Army Institute of Surgical Research
- United States Army Medical Research and Development Command
- University of Texas at San Antonio