The contribution of oxidative stress to platelet senescence during storage

Abstract

Platelets for transfusion become senescent and dysfunctional during storage, resulting in a markedly short shelf life (5 days). We hypothesized that oxidative stress might account for this decline.

Document Details

Document Type
Pub Defense Publication
Publication Date
Apr 03, 2019
Source ID
10.1111/trf.15291

Entities

People

  • Jie Yang
  • Li Wang
  • Mei X Wu
  • Qiang Wu
  • Rufeng Xie
  • Wei Liang
  • Yuan Lu
  • Zhicheng Wang
  • Zhijia Fan

Organizations

  • Fudan University
  • Harvard Medical School
  • National Natural Science Foundation of China
  • United States Department of Defense

Tags

Readers

  • Immunology and Pathology
  • Trauma Surgery or Emergency Medicine.