Prehospital whole blood resuscitation prevents coagulopathy and improves acid–base status at hospital arrival in a nonhuman primate hemorrhagic shock model
Abstract
Hemorrhage remains the primary cause of preventable death in civilian and military trauma. The Committee on Tactical Combat Casualty Care recommends prehospital (PH) resuscitation with whole blood (WB). However, 6% hetastarch in lactated electrolyte (HEX) and crystalloids are more commonly available and used for PH resuscitation in military and civilian environments, respectively. The mechanistic benefits of PH WB resuscitation have not been well studied and remain to be elucidated.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 03, 2019
- Source ID
- 10.1111/trf.15294
Entities
People
- Andrew P Cap
- Antoni R. Macko
- Forest R. Sheppard
- Jacob J. Glaser
- Leasha J. Schaub
- Thomas A. Mitchell
Organizations
- Maine Medical Center
- Naval Medical Research Unit—San Antonio
- Office of Naval Research
- United States Army Institute of Surgical Research