Traumatic injury results in prolonged circulation of ultralarge von Willebrand factor and a reduction in ADAMTS13 activity
Abstract
Increases in plasma von Willebrand Factor (VWF) levels, accompanied by decreases in the metalloprotease ADAMTS13, have been demonstrated soon after traumatic injury while downstream effects remain unclear.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 22, 2020
- Source ID
- 10.1111/trf.15856
Entities
People
- A Tactic Publication
- Brian S. Zuckerbraun
- Francis X. Guyette
- Jason Lee Sperry
- Jay S Raval
- Margaret V. Ragni
- Marian A. Rollins‐raval
- Matthew D Neal
- Mitchell R. Dyer
- Shannon Haldeman
- William E Plautz
- Wyeth Alexander
Organizations
- Alpha Omega Alpha
- National Institutes of Health Clinical Center
- United States Army Medical Research and Development Command
- University of New Mexico
- University of North Carolina at Chapel Hill
- University of Pittsburgh
- University of Pittsburgh School of Medicine