Characterization and first‐in‐human clinical dose‐escalation safety evaluation of a next‐gen human freeze‐dried plasma
Abstract
Early plasma transfusion is life‐saving for bleeding trauma patients. Freeze‐dried plasma (FDP) provides unique formulation advantages for infusion in the prehospital setting. We describe characterization and clinical safety data of the first, next‐generation FDP stored in plastic bags with rapid reconstitution.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 24, 2021
- Source ID
- 10.1111/trf.16756
Entities
People
- Andrew J. Atkinson
- Anna Eckerman
- David Burgess
- James Murto
- Joan C. Pehta
- Jose A Cancelas
- Luke Markstrom
- Manoj K. Valiyaveettil
- Matthew L. Charles
- Melissa R. King
- Michele Snyder
- Neeta Rugg
- Shawnagay Nestheide
- Stephen A. Penegor
- Victor W. Macdonald
Organizations
- United States Department of Defense
- University of Cincinnati
- Westat