Comparison of platelet quality and function across apheresis collection platforms

Abstract

Platelet concentrates (PLT) can be manufactured using a combination of apheresis collection devices and suspension media (plasma or platelet additive solution (PAS)). It is unclear how platelet quality and hemostatic function differ across the current in‐use manufacturing methods in the United States. The objective of this study was therefore to compare baseline function of PLT collected using different apheresis collection platforms and storage media.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 01, 2023
Source ID
10.1111/trf.17370

Entities

People

  • Alexandra Smith
  • Amudan J. Srinivasan
  • Andrew P Cap
  • Colby Mcintosh
  • James A. Bynum
  • Javonn Musgrove
  • Katelin Rahn
  • Kennedy S. Mdaki
  • Kimberly A Thomas
  • Kristin M Reddoch-Cardenas
  • Lilian Mcgough
  • Lisa Vavro
  • M. Adam Meledeo
  • Philip C Spinella
  • Ronnie Hill
  • Samantha Perez
  • Scott Kelly
  • Skye Clayton
  • Susan M Hastings

Organizations

  • United States Army Institute of Surgical Research
  • United States Department of Defense
  • University of Pittsburgh
  • University of Texas at Austin

Tags

Readers

  • Aerosol Science/Aerosol Physics
  • Manufacturing Engineering.
  • Trauma Surgery or Emergency Medicine.