Hormesis mediates platelet‐rich plasma and wound healing
Abstract
Platelet‐rich plasma (PRP) has become an accepted and general wound healing approach with an extremely wide range of applications. Despite considerable diversity in the composition of platelet‐rich plasma products that are applied in specific wound healing usage, it is widely recognised that such diverse platelet‐rich plasma complex mixtures routinely display hormetic‐like biphasic concentrations that are independent of the tissue treated and endpoints measured. The present paper is the first to place the area of platelet‐rich plasma‐biomedical research and applications within an hormetic framework. The platelet‐rich plasma area is also unique as it represents the application of the hormetic concept to the issue of complex biological mixtures.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 09, 2022
- Source ID
- 10.1111/wrr.13060
Entities
People
- Edward Calabrese
- Gaurav Dhawan
- Rachna Kapoor
- Vittorio Calabrese
Organizations
- Air Force Office of Scientific Research
- Saint Francis Hospital & Medical Center
- University of Catania
- University of Health Sciences, Lahore
- University of Massachusetts