Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes
Abstract
Traumatic brain injury (TBI) is an acquired brain injury that occurs when there is sudden trauma that leads to brain damage. This acute complex event can happen when the head is violently or suddenly struck or an object pierces the skull or brain. The current principal treatment of TBI includes various pharmaceutical agents, hyperbaric oxygen, and hypothermia. There is evidence that secondary injury from a TBI is specifically related to oxidative stress. However, the clinical management of TBI often does not include antioxidants to reduce oxidative stress and prevent secondary injury.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 31, 2016
- Source ID
- 10.1111/wvn.12167
Entities
People
- Amanda R. Thimmesch
- Janet D. Pierce
- John B. Hiebert
- Julie Hartwell
- Qiuhua Shen
Organizations
- Uniformed Services University of the Health Sciences
- University of Kansas