In vitro exposure of pig neonatal isletlike cell clusters to human blood

Abstract

Pig islet grafts have been successful in treating diabetes in animal models. One remaining question is whether neonatal pig isletlike cell clusters (NICC) are resistant to the early loss of islets from the instant blood‐mediated inflammatory reaction (IBMIR).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 01, 2015
Source ID
10.1111/xen.12178

Entities

People

  • David Ayares
  • David K.C. Cooper
  • Gina R. Rayat
  • Hidetaka Hara
  • Martin Wijkstrom
  • Massimo Trucco
  • Rita Bottino
  • Santosh Nagaraju
  • Suzanne Bertera
  • Takayuki Tanaka

Organizations

  • JDRF
  • National Institutes of Health
  • United Therapeutics
  • University of Alberta
  • University of Pittsburgh

Tags

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular and Cellular Biology