Peptide interactions with zigzag edges in graphene

Abstract

Recognition and manipulation of graphene edges enable the control of physical properties of graphene-based devices. Recently, the authors have identified a peptide that preferentially binds to graphene edges from a combinatorial peptide library. In this study, the authors examine the functional basis for the edge binding peptide using experimental and computational methods. The effect of amino acid substitution, sequence context, and solution pH value on the binding of the peptide to graphene has been investigated. The N-terminus glutamic acid residue plays a key role in recognizing and binding to graphene edges. The protonation, substitution, and positional context of the glutamic acid residue impact graphene edge-binding. Our findings provide insights into the binding mechanisms and the design of peptides for recognizing and functionalizing graphene edges.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 04, 2016
Source ID
10.1116/1.4966266

Entities

People

  • Barry L. Farmer
  • Michael McAlpine
  • Rajesh R Naik
  • Steve S. Kim
  • Yen H. Ngo
  • Zhifeng Kuang

Organizations

  • 711th Human Performance Wing
  • Air Force Office of Scientific Research
  • Air Force Research Laboratory Materials and Manufacturing Directorate
  • University of Minnesota

Tags

Readers

  • Breast cancer cell signaling and growth regulation.
  • Computer Vision.
  • Nanocomposite Materials Science

Technology Areas

  • Microelectronics
  • Microelectronics - Graphene