Solid‐tumor radionuclide therapy dosimetry: New paradigms in view of tumor microenvironment and angiogenesis
Abstract
The objective of this study is to evaluate requirements for radionuclide‐based solid tumor therapy by assessing the radial dose distribution of beta‐particle‐emitting and alpha‐particle‐emitting molecules localized either solely within endothelial cells of tumor vasculature or diffusing from the vasculature throughout the adjacent viable tumor cells.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 01, 2010
- Source ID
- 10.1118/1.3431999
Entities
People
- Amin I. Kassis
- G. Mike Makrigiorgos
- Matthew R. Palmer
- Xuping Zhu
Organizations
- National Institutes of Health
- United States Department of Defense