MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs

Abstract

MED12 is methylated by CARM1, and methylated MED12 serves as a sensor for anticancer drug response in human breast cancer.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Oct 02, 2015
• Source ID: 10.1126/sciadv.1500463

Entities

People

• Hao Zeng
• Lu Wang
• Qiang Wang
• Thomas G. Boyer
• Wei Xu
• Xiuwu Bian
• Zibo Zhao

Organizations

• Army Medical University
• United States Department of Defense
• University of Texas Health Science Center at San Antonio
• University of Wisconsin–Madison

Tags

Readers

• Breast cancer cell signaling and growth regulation.
• Molecular and genetic basis of cancer.