Subtle balance of tropoelastin molecular shape and flexibility regulates dynamics and hierarchical assembly

Abstract

Tropoelastin’s local and global structures dictate molecular dynamics and are essential for efficient assembly into elastin.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 05, 2016
Source ID
10.1126/sciadv.1501145

Entities

People

  • Anna Tarakanova
  • Anthony S. Weiss
  • Clair Baldock
  • Giselle C. Yeo
  • Markus J. Buehler
  • Steven G. Wise

Organizations

  • Australian Research Council
  • Biotechnology and Biological Sciences Research Council
  • Heart Research Institute
  • Massachusetts Institute of Technology
  • National Health and Medical Research Council
  • National Institutes of Health
  • Office of Naval Research
  • University of Manchester
  • University of Sydney
  • Wellcome Trust

Tags

Fields of Study

  • Chemistry

Readers

  • Computational Fluid Dynamics (CFD)
  • Molecular and Cellular Biochemistry
  • Theoretical Analysis.