Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix
Abstract
This study demonstrates targeting of blood-brain barrier disruption to deliver payloads at sites of neurological disease.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 03, 2019
- Source ID
- 10.1126/sciadv.aau4245
Entities
People
- Benjamin J Umlauf
- Brantley R Herrin
- Eric V Shusta
- Jason M. Lajoie
- John S. Kuo
- Julia V. Georgieva
- Paul A Clark
- Samantha Bremner
Organizations
- Defense Threat Reduction Agency
- Dr. Ralph and Marian Falk Medical Research Trust
- Emory University
- National Institutes of Health
- University of Texas at Austin
- University of Wisconsin–Madison