Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties

Abstract

The authors differentiate human stem cells to brain pericyte–like cells and integrate them into a neurovascular unit model.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 01, 2019
Source ID
10.1126/sciadv.aau7375

Entities

People

  • Benjamin D. Gastfriend
  • Drew Richards
  • Eric V Shusta
  • Madeline G. Faubion
  • Matthew J Stebbins
  • Ming-song Lee
  • Richard Daneman
  • Scott G Canfield
  • Sean P Palecek
  • Wan-ju Li

Organizations

  • Defense Threat Reduction Agency
  • National Institute of Neurological Disorders and Stroke
  • University of California, San Diego
  • University of Wisconsin–Madison

Tags

Readers

  • Immunology and Pathology
  • Neuroscience
  • Systems Analysis and Design

Technology Areas

  • Biotechnology