Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes

Abstract

Natural triterpenoids, as virus-host fusion inhibitors, exhibit potential in expanding the current repertoire of antiviral agents.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 02, 2018
Source ID
10.1126/sciadv.aau8408

Entities

People

  • Demin Zhou
  • Ge Fu
  • Haiwei Li
  • Huiqiang Li
  • Jiaqi Sun
  • Kun Meng
  • Lihe Zhang
  • Longlong Si
  • Qing Xia
  • Sulong Xiao
  • Veronica Soloveva
  • Zhenyu Tian
  • Ziwei Zhang

Organizations

  • National Natural Science Foundation of China
  • Peking University
  • Program 973
  • United States Army Medical Research Institute of Infectious Diseases

Tags

Readers

  • Distributed Systems and Data Platform Development
  • Reinforced Composite Materials
  • Virology (or Medical Virology).