Inflammation up-regulates cochlear expression of TRPV1 to potentiate drug-induced hearing loss
Abstract
The nonselective cation channel TRPV1 is required for systemic inflammation to enhance aminoglycoside-induced hearing loss.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 05, 2019
- Source ID
- 10.1126/sciadv.aaw1836
Entities
People
- Allan Kachelmeier
- Anastasiya Johnson
- Farshid Taghizadeh
- Hongzhe Li
- Meiyan Jiang
- Peter S Steyger
- Takatoshi Karasawa
- William B Meier
- Yuan Zhang
Organizations
- National Institute on Deafness and Other Communication Disorders
- United States Department of Defense