Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

Abstract

Single-cell RNA-Seq reveals smoking-induced bronchial cell type–specific alterations and a novel peri-goblet cell.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Dec 06, 2019
• Source ID: 10.1126/sciadv.aaw3413

Entities

People

• Avrum Spira
• Corry-Anke Brandsma
• Gang Liu
• Grant E Duclos
• Jennifer Beane
• Joshua D Campbell
• Maarten Van Den Berge
• Marc E. Lenburg
• Marjan A. Reinders-luinge
• Patrick Autissier
• Robert Terrano
• Sam M Janes
• Sarah A Mazzilli
• Vitor H Teixeira
• Wim Timens
• Yaron B. Gesthalter
• Yves M. Dumas

Organizations

• Boston University
• LUNGevity Foundation
• National Institutes of Health
• United States Department of Defense
• University College Hospital
• University College London
• University of California, San Francisco
• University of Groningen