High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA

Abstract

A chemical approach enables the rapid mapping of CoA metabolites in complex biological systems.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jun 01, 2019
• Source ID: 10.1126/sciadv.aaw9180

Entities

People

• Aislinn K McMillan
• Michael C Jewett
• Milan Mrksich
• Patrick T O'Kane
• Quentin M Dudley

Organizations

• Air Force Research Laboratory
• David and Lucile Packard Foundation
• Defense Threat Reduction Agency
• Northwestern University
• United States Department of Energy