Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing
Abstract
Covalently tethering RNA to hydrogel provides the prolonged presentation of RNA for locally sustained cellular gene silencing.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 02, 2019
- Source ID
- 10.1126/sciadv.aax0801
Entities
People
- Alex Gilewski
- Cong Truc Huynh
- Eben Alsberg
- Keith E Maier
- Mathew Levy
- Minh Khanh Nguyen
- Nicholas Kwon
- Samantha E Wilner
Organizations
- Albert Einstein College of Medicine
- Case Western Reserve University
- Congressionally Directed Medical Research Programs
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Institute of Dental and Craniofacial Research