In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Abstract

CCL22-releasing microparticles recruit suppressive immune cells to transplanted rat limbs to promote long-term graft survival.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 13, 2020
Source ID
10.1126/sciadv.aax8429

Entities

People

  • Abhinav P. Acharya
  • Ali Mubin Aral
  • Angus W. Thomson
  • Heth Turnquist
  • James D Fisher
  • Jingjing Li
  • Mario Solari
  • Stephen C Balmert
  • Steven R. Little
  • Vijay S Gorantla
  • Wensheng Zhang
  • Yalçın Külahçı

Organizations

  • National Cancer Institute
  • National Institute of Allergy and Infectious Diseases
  • National Institute of Dental and Craniofacial Research
  • United States Department of Defense
  • University of Pittsburgh
  • Wake Forest School of Medicine

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Aerosol Science/Aerosol Physics
  • Neuroscience
  • Oncology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech