Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues
Abstract
Denatured collagen accumulates during cyclic fatigue loading and explains the micro-damage hypothesis of overuse tissue injury.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 28, 2020
- Source ID
- 10.1126/sciadv.aba2795
Entities
People
- Allen H Lin
- Gang Seob Jung
- Jared L Zitnay
- Jeffrey A. Weiss
- Markus J. Buehler
- S Michael Yu
- Yang Li
- Zhao Qin
Organizations
- Massachusetts Institute of Technology
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Institute of Biomedical Imaging and Bioengineering
- Office of Naval Research
- University of Utah